Description

5-Bromo-2-Morpholinopyrimidine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate of significant importance in modern drug discovery and development. This compound serves as a critical building block for the synthesis of complex molecules, particularly kinase inhibitors and other targeted therapeutics. It is essential for research and production teams in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality raw materials for their synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitor drugs targeting various cancers and inflammatory diseases.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies to develop novel therapeutic agents.
• Chemical Biology Probes: Employed in the development of chemical probes to study specific biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for custom synthesis projects and scale-up manufacturing under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic and organic chemistry.

Basic Information

Product Name	5-Bromo-2-Morpholinopyrimidine-4-Carboxylic Acid
CAS No.	914208-35-8
Molecular Formula	C9H10BrN3O3
Molecular Weight	288.10 g/mol
Synonyms	5-Bromo-2-morpholin-4-ylpyrimidine-4-carboxylic acid; 4-Pyrimidinecarboxylic acid, 5-bromo-2-(4-morpholinyl)-; 2-Morpholino-5-bromopyrimidine-4-carboxylic acid; 5-Bromo-2-(morpholin-4-yl)pyrimidine-4-carboxylic acid; 914208-35-8; 5-Bromo-2-morpholin-4-yl-4-pyrimidinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Morpholinopyrimidine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with the standards expected for pharmaceutical intermediates, supporting our clients' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.