Description

4-Cyclopropyl-2-(Trifluoromethyl)Pyrimidine-5-Carboxylic Acid is a high-value pyrimidine carboxylic acid derivative, distinguished by its cyclopropyl and trifluoromethyl functional groups which confer unique steric and electronic properties. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, leveraging the biological activity of the pyrimidine core.
• Chemical Research & Development: Serves as a sophisticated building block for constructing complex heterocyclic compounds in medicinal and process chemistry.
• Material Science: Potential applications in the development of specialty polymers and organic electronic materials due to its aromatic and fluorinated structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	4-Cyclopropyl-2-(Trifluoromethyl)Pyrimidine-5-Carboxylic Acid
CAS No.	914201-19-7
Molecular Formula	C9H7F3N2O2
Molecular Weight	232.16 g/mol
Synonyms	4-Cyclopropyl-2-(trifluoromethyl)-5-pyrimidinecarboxylic acid; 2-(Trifluoromethyl)-4-cyclopropylpyrimidine-5-carboxylic acid; 5-Pyrimidinecarboxylic acid, 4-cyclopropyl-2-(trifluoromethyl)-; 4-Cyclopropyl-2-trifluoromethyl-pyrimidine-5-carboxylic acid; 914201-19-7; 4-Cyclopropyl-2-(trifluoromethyl)pyrimidine-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 4-Cyclopropyl-2-(Trifluoromethyl)Pyrimidine-5-Carboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and commercial projects requiring compliance with cGMP and ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.