Description

4-Chloro-6-(2-Cyanophenoxy)-Pyrimidine is a high-value pyrimidine derivative, serving as a critical advanced pharmaceutical intermediate for the synthesis of complex active ingredients. Its unique structure, featuring both chloro and cyanophenoxy substituents, makes it an essential building block for medicinal chemistry research and development. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries to create novel drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, leveraging its heterocyclic core.
• Chemical Research & Development: Serves as a versatile scaffold for structure-activity relationship (SAR) studies in medicinal chemistry.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the multi-step synthesis of complex APIs under controlled GMP conditions.
• Custom Synthesis & Contract Manufacturing: A requested compound for bespoke synthesis projects in fine chemical production.
• Material Science Research: Investigated as a potential monomer or building block for specialty polymers and functional materials.

Basic Information

Product Name	4-Chloro-6-(2-Cyanophenoxy)-Pyrimidine
CAS No.	913846-53-4
Molecular Formula	C11H6ClN3O
Molecular Weight	231.64 g/mol
Synonyms	4-Chloro-6-(2-cyanophenoxy)pyrimidine; 6-(2-Cyanophenoxy)-4-chloropyrimidine; 4-Chloro-6-(o-cyanophenoxy)pyrimidine; Pyrimidine, 4-chloro-6-(2-cyanophenoxy)-; 913846-53-4; 4-Chloro-6-(2-cyanophenoxy)pyrimidine (CAS 913846-53-4); 2-(4-Chloropyrimidin-6-yloxy)benzonitrile
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-(2-Cyanophenoxy)-Pyrimidine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. Certificates of Analysis (COA) are provided with every shipment, detailing all specifications and test results to ensure traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.