Description

4-((4-(Aminomethyl)Benzyl)Oxy)-6-Chloropyrimidin-2-Amine is a high-purity, functionalized pyrimidine derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and critical building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other enzyme-related pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators due to its bioactive pyrimidine core.
• Ligand Synthesis: The aminomethyl and amine functional groups make it suitable for creating chelating ligands in catalysis or metal-organic frameworks (MOFs).
• Peptide Mimetics & Conjugates: Employed in medicinal chemistry for constructing peptide-like structures or antibody-drug conjugate (ADC) linkers.
• Material Science: Acts as a monomer or cross-linking agent for synthesizing specialized polymers with unique thermal or mechanical properties.
• Chemical Biology Probes: Utilized to develop molecular probes for studying biological processes and target identification.

Basic Information

Product Name	4-((4-(Aminomethyl)Benzyl)Oxy)-6-Chloropyrimidin-2-Amine
CAS No.	913817-45-5
Molecular Formula	C12H13ClN4O
Molecular Weight	264.71 g/mol
Synonyms	6-Chloro-4-[[4-(aminomethyl)phenyl]methoxy]-2-pyrimidinamine; 4-((4-(Aminomethyl)benzyl)oxy)-6-chloro-2-pyrimidinamine; 2-Amino-6-chloro-4-[(4-aminomethylbenzyl)oxy]pyrimidine; 6-Chloro-4-[(4-aminomethylbenzyl)oxy]pyrimidin-2-ylamine; 913817-45-5; 4-(4-Aminomethyl-benzyloxy)-6-chloro-pyrimidin-2-ylamine
EINECS	Contact for details

Quality Control

Every batch of 4-((4-(Aminomethyl)Benzyl)Oxy)-6-Chloropyrimidin-2-Amine undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality management system is designed to meet the stringent requirements of research and pre-clinical development. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (by IR, NMR), and impurity profiles is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.