Description

4-Methyl-6-(2-Iodo-5-Fluorophenyl)Pyrimidin-2-Amine is a high-purity, halogenated pyrimidine derivative, a key building block in advanced organic synthesis. This compound matters for its role as a crucial intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific substitution pattern enables targeted molecular design. It is primarily needed by research and development chemists, process development teams, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging its halogenated aromatic structure.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and liquid crystals due to its rigid, conjugated core.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Reference Standard: Used as an analytical standard for quality control and regulatory filings in pharmaceutical manufacturing.

Basic Information

Item	Details
Product Name	4-Methyl-6-(2-Iodo-5-Fluorophenyl)Pyrimidin-2-Amine
CAS No.	913322-53-9
Molecular Formula	C11H9FIN3
Molecular Weight	329.11 g/mol
Synonyms	2-Amino-4-methyl-6-(2-iodo-5-fluorophenyl)pyrimidine; 6-(2-Iodo-5-fluorophenyl)-4-methylpyrimidin-2-amine; 4-Methyl-6-(2-iodo-5-fluorophenyl)-2-pyrimidinamine; 913322-53-9; 4-Methyl-6-(2-iodo-5-fluorophenyl)-2-aminopyrimidine; 2-Pyrimidinamine, 6-(2-iodo-5-fluorophenyl)-4-methyl-; 4-Methyl-6-(2-iodo-5-fluorophenyl)-2-pyrimidinylamine
EINECS	Contact for details

Quality Control

Our 4-Methyl-6-(2-Iodo-5-Fluorophenyl)Pyrimidin-2-Amine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.