Description

4-Methyl-6-(2-Fluorophenyl)Pyrimidin-2-Amine CAS NO 913322-50-6 is a high-purity, functionalized pyrimidine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific substitution pattern is essential for biological activity. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging its pyrimidine core for bioactivity.
• Material Science Research: Serves as a monomer or functional additive in the development of specialty polymers and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a scaffold or tagging agent in the design of molecular probes and enzyme inhibitors for biochemical studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific synthesis projects requiring high-purity, complex heterocycles.

Basic Information

Product Name	4-Methyl-6-(2-Fluorophenyl)Pyrimidin-2-Amine
CAS No.	913322-50-6
Molecular Formula	C11H10FN3
Molecular Weight	203.22 g/mol
Synonyms	2-Amino-4-methyl-6-(2-fluorophenyl)pyrimidine; 6-(2-Fluorophenyl)-4-methylpyrimidin-2-amine; 4-Methyl-6-(o-fluorophenyl)-2-pyrimidinamine; 2-Pyrimidinamine, 6-(2-fluorophenyl)-4-methyl-; 913322-50-6; 4-Methyl-6-(2-fluorophenyl)-2-aminopyrimidine
EINECS	Contact for details

Quality Control

Our production of 4-Methyl-6-(2-Fluorophenyl)Pyrimidin-2-Amine adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. Each lot undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We operate under a cGMP-compliant quality system suitable for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.