Description

Adrenomedullin (Porcine) is a bioactive peptide hormone derived from porcine origin, identified by CAS NO 912862-96-5. This compound is a critical research tool for studying cardiovascular regulation, vasodilation, and its role in inflammatory and septic shock models. It is essential for pharmaceutical R&D, academic research, and biotechnology applications focused on peptide therapeutics and cardiovascular disease mechanisms.

Application

• Biomedical Research: Used as a reference standard in studies investigating vasodilation, blood pressure regulation, and endothelial function.
• Pharmaceutical Development: Serves as a key intermediate or reference material in the R&D of novel cardiovascular and anti-inflammatory drugs.
• Diagnostic Assay Development: Employed in the calibration and validation of immunoassays (ELISA, RIA) designed to detect adrenomedullin levels.
• Cell Culture & In Vitro Studies: Applied in cell-based assays to study receptor binding, signal transduction pathways, and cellular responses.
• Academic & Clinical Research: Fundamental for exploring the peptide's role in conditions like hypertension, heart failure, sepsis, and cancer.
• Peptide Chemistry & Synthesis: Used as a benchmark for purity and activity in custom peptide synthesis and structure-activity relationship (SAR) studies.

Basic Information

Product Name	Adrenomedullin (Porcine)
CAS No.	912862-96-5
Molecular Formula	C164H256N50O49S2
Molecular Weight	~3740.3 g/mol
Synonyms	Porcine Adrenomedullin; ADM (Porcine); Preproadrenomedullin (153-185) (porcine); AM (Porcine); Adrenomedullin, porcine; ADM-52 (porcine); H-Tyr-Arg-Gln-Ser-Met-Asn-Asn-Phe-Gln-Gly-Leu-Arg-Ser-Phe-Gly-Cys-Arg-Phe-Gly-Thr-Cys-Thr-Val-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Asn-Val-Ala-Pro-Arg-Ser-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2 (Disulfide bridge: Cys16-Cys21)
EINECS	Contact for details

Quality Control

Our Adrenomedullin (Porcine) is produced under stringent conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing purity, peptide content, and analytical results are provided to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	Conforms to theoretical composition
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, acetic acid, or DMSO
Biological Activity	Assayed by vasodilation or receptor binding (Contact for details)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.