Description

3(2H)-Benzofuranone, 4-Fluoro- is a high-purity fluorinated organic intermediate of significant importance in advanced chemical synthesis. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used to develop new-generation herbicides and fungicides with enhanced efficacy and environmental profiles.
• Material Science: Building block for creating specialty polymers and liquid crystals with unique optical or electronic properties.
• Organic Synthesis Research: Valuable reagent for introducing the benzofuranone scaffold with a fluorine substituent in medicinal chemistry and process development.
• Fluorine Chemistry Studies: Serves as a model compound for studying the reactivity and effects of fluorine in heterocyclic systems.

Basic Information

Product Name	3(2H)-Benzofuranone, 4-Fluoro-
CAS No.	911826-36-3
Molecular Formula	C8H5FO2
Molecular Weight	152.12 g/mol
Synonyms	4-Fluoro-3(2H)-benzofuranone; 4-Fluorobenzofuran-3(2H)-one; 4-Fluoro-2,3-dihydro-1-benzofuran-3-one; 4-Fluoro-3-coumaranone; 4-Fluorophthalide (Note: structural isomer); 911826-36-3; 4-Fluoro-2,3-dihydrobenzofuran-3-one
EINECS	Contact for details

Quality Control

Our production of 4-Fluoro-3(2H)-benzofuranone adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting cGMP and ISO 9001 compliance for our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.