Description

(2-Fluoro-6-Iodophenyl)Methanol is a versatile fluorinated and iodinated benzyl alcohol derivative, serving as a critical building block in advanced organic synthesis. Its unique bifunctional structure, featuring both fluorine and iodine substituents, makes it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry, ligand synthesis, and the development of novel materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and metabolic stability.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The iodine moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl structures.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for imaging and diagnostic applications.

Basic Information

Product Name	(2-Fluoro-6-Iodophenyl)Methanol
CAS No.	911825-94-0
Molecular Formula	C7H6FIO
Molecular Weight	252.03 g/mol
Synonyms	2-Fluoro-6-iodobenzyl alcohol; (2-Fluoro-6-iodophenyl)methanol; 1-(2-Fluoro-6-iodophenyl)methanol; α-Hydroxymethyl-2-fluoro-6-iodobenzene; 2-Fluoro-6-iodo-benzenemethanol; Benzenemethanol, 2-fluoro-6-iodo-; (2-Fluoro-6-iodo-phenyl)-methanol
EINECS	Contact for details

Quality Control

Our (2-Fluoro-6-Iodophenyl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature, the container should be amber-colored or stored in a dark environment. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.