Description

4-Chloro-5-Iodo-7-((4-Methoxy-3,5-Dimethylpyridin-2-Yl)Methyl)-7H-Pyrrolo[2,3-D]Pyrimidin-2-Amine is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of targeted therapeutic agents. This compound is critical for research and development in medicinal chemistry, particularly for programs focused on kinase inhibition. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel kinase inhibitor candidates for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• Preclinical Development: Serves as a critical starting material for producing compounds for pharmacological and toxicological evaluation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and drug discovery.
• Process Chemistry: Investigated for scalable synthetic routes in the development of cost-effective manufacturing processes for potential APIs.

Basic Information

Product Name	4-Chloro-5-Iodo-7-((4-Methoxy-3,5-Dimethylpyridin-2-Yl)Methyl)-7H-Pyrrolo[2,3-D]Pyrimidin-2-Amine
CAS No.	911397-54-1
Molecular Formula	C15H15ClIN5O
Molecular Weight	443.67 g/mol
Synonyms	4-Chloro-5-iodo-7-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]-7H-pyrrolo[2,3-d]pyrimidin-2-amine; 7-((4-Methoxy-3,5-dimethylpyridin-2-yl)methyl)-4-chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-2-amine; 4-Chloro-5-iodo-7-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine; Kinase Inhibitor Intermediate; Pyrrolopyrimidine Derivative; CAS 911397-54-1
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Iodo-7-((4-Methoxy-3,5-Dimethylpyridin-2-Yl)Methyl)-7H-Pyrrolo[2,3-D]Pyrimidin-2-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.