Description

6-Chloro-2-Fluoro Benzylamine is a versatile fluorinated aromatic amine building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both chloro and fluoro substituents on the benzylamine core, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to introduce key pharmacophores and modulate the bioactivity, metabolic stability, and physical characteristics of target compounds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of new drugs targeting central nervous system disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and chlorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials due to its ability to influence electronic properties and intermolecular interactions.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom chemical synthesis services catering to R&D and pilot-scale production needs.

Basic Information

Product Name	6-Chloro-2-Fluoro Benzylamine
CAS No.	911300-69-1
Molecular Formula	C7H7ClFN
Molecular Weight	159.59 g/mol
Synonyms	(6-Chloro-2-fluorophenyl)methanamine; 1-(6-Chloro-2-fluorophenyl)methanamine; 2-Fluoro-6-chlorobenzylamine; Benzenemethanamine, 6-chloro-2-fluoro-; 6-Chloro-2-fluoro-benzenemethanamine; 2-Chloro-6-fluorobenzylamine (isomer); α-Amino-6-chloro-2-fluorotoluene
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-Fluoro Benzylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its amine functionality and light-sensitive nature, prolonged exposure to light or air should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.