Description

6-Amino-1-(3-Methoxyphenyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrimidine-dione core functionalized with an aldehyde group. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of small molecule therapeutics, particularly for applications in oncology and antiviral research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel heterocyclic compounds for drug discovery programs.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Organic Synthesis Building Block: The reactive aldehyde and amino groups facilitate further chemical modifications, such as condensation and cyclization reactions.
• Biochemical Research: Potential use in developing enzyme inhibitors or probes due to its specific molecular architecture.
• Contract Manufacturing (CMO): Supplied to custom synthesis organizations for the production of active pharmaceutical ingredients (APIs) under cGMP conditions.

Basic Information

Product Name	6-Amino-1-(3-Methoxyphenyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde
CAS No.	910443-02-6
Molecular Formula	C₁₂H₁₁N₃O₄
Molecular Weight	261.24 g/mol
Synonyms	6-Amino-1-(3-methoxyphenyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxaldehyde; 5-Formyl-6-amino-1-(3-methoxyphenyl)uracil; 1-(3-Methoxyphenyl)-6-amino-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde; 6-Amino-1-(3-methoxyphenyl)-5-formyluracil; 910443-02-6; 6-Amino-1-(3-methoxyphenyl)uracil-5-carbaldehyde; 5-Carbaldehyde-6-amino-1-(3-methoxyphenyl)-2,4(1H,3H)-pyrimidinedione
EINECS	Contact for details

Quality Control

Our 6-Amino-1-(3-Methoxyphenyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay (HPLC), related substances, and residual solvents. Our quality commitment supports compliance with ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.