Description

1-(3-Bromo-4-Fluorophenyl)Propan-2-Amine is a high-purity, halogenated aromatic amine building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both bromine and fluorine substituents, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and pharmaceutical companies for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the halogenated phenyl group contributes to biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis for asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific optoelectronic properties.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological systems and mechanisms.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses serving the pharmaceutical and biotechnology industries.

Basic Information

Product Name	1-(3-Bromo-4-Fluorophenyl)Propan-2-Amine
CAS No.	910383-85-6
Molecular Formula	C9H11BrFN
Molecular Weight	232.09 g/mol
Synonyms	1-(3-Bromo-4-fluorophenyl)-2-propanamine; 1-(3-Bromo-4-fluorophenyl)propan-2-amine; 3-Bromo-4-fluoroamphetamine; 3-Bromo-4-fluoro-α-methylphenethylamine; 4-Fluoro-3-bromoamphetamine; 4-Fluoro-3-bromo-α-methylphenethylamine; BFA; 910383-85-6
EINECS	Contact for details

Quality Control

Our production of 1-(3-Bromo-4-Fluorophenyl)Propan-2-Amine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC-MS, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.