Description

4-[6-[[5-[[(2-Chloro-6-Methylphenyl)Amino]Carbonyl]-2-Thiazolyl]Amino]-2-Methyl-4-Pyrimidinyl]-1-Piperazineacetic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of targeted therapeutic agents, particularly in oncology research. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of investigational drug candidates, especially kinase inhibitors.
• Oncology Research: Used in the discovery and development of targeted cancer therapies due to its specific molecular scaffold.
• Biochemical Research: Serves as a reference standard or a tool compound in pharmacological studies and mechanism-of-action research.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex molecules for biological screening.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of clinical trial materials (CTM).
• Academic Research: Utilized in university and institutional labs for medicinal chemistry and drug design projects.

Basic Information

Product Name	4-[6-[[5-[[(2-Chloro-6-Methylphenyl)Amino]Carbonyl]-2-Thiazolyl]Amino]-2-Methyl-4-Pyrimidinyl]-1-Piperazineacetic Acid Ethyl Ester
CAS No.	910297-62-0
Molecular Formula	C24H28ClN7O3S
Molecular Weight	530.05 g/mol
Synonyms	Ethyl 4-[6-[[5-[[(2-chloro-6-methylphenyl)carbamoyl]-1,3-thiazol-2-yl]amino]-2-methylpyrimidin-4-yl]piperazine-1-acetate; UNII-9J2U8I7D8C; 9J2U8I7D8C; 4-[6-[[5-[[(2-Chloro-6-Methylphenyl)Amino]Carbonyl]-2-Thiazolyl]Amino]-2-Methyl-4-Pyrimidinyl]-1-Piperazineacetic Acid Ethyl Ester; BMS-777607 intermediate; AS-252424 analog; TAM kinase inhibitor intermediate
EINECS	Contact for details

Quality Control

Our production of 4-[6-[[5-[[(2-Chloro-6-Methylphenyl)Amino]Carbonyl]-2-Thiazolyl]Amino]-2-Methyl-4-Pyrimidinyl]-1-Piperazineacetic Acid Ethyl Ester adheres to stringent quality systems. Every batch is characterized and tested using advanced analytical techniques (HPLC, NMR, MS) to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.