Description

4-Methoxy-2-[4-(1-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Piperidin-4-Yl)Piperazin-1-Yl]Pyrimidine is a sophisticated heterocyclic compound featuring a pyrimidine core linked to a piperazine-piperidine scaffold with a trifluoromethylpyridine moiety. This complex structure makes it a high-value intermediate for advanced pharmaceutical research and development, particularly in the discovery of novel therapeutics. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in synthesizing targeted bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Biochemical Tool Compound: Serves as a reference standard or probe in pharmacological assays to study specific biological pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Active Pharmaceutical Ingredient (API) Development: Employed in the development and scale-up of new active pharmaceutical ingredients.

Basic Information

Item	Detail
Product Name	4-Methoxy-2-[4-(1-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Piperidin-4-Yl)Piperazin-1-Yl]Pyrimidine
CAS No.	909670-75-3
Molecular Formula	C21H26F3N5O
Molecular Weight	421.46 g/mol
Synonyms	4-Methoxy-2-[4-[1-[[6-(trifluoromethyl)-3-pyridinyl]methyl]-4-piperidinyl]-1-piperazinyl]pyrimidine; 2-(4-(1-((6-(Trifluoromethyl)pyridin-3-yl)methyl)piperidin-4-yl)piperazin-1-yl)-4-methoxypyrimidine; 909670-75-3; UNII-4V3K4K8J4K; 4-Methoxy-2-(4-(1-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperidin-4-yl)piperazin-1-yl)pyrimidine; CHEMBL3186668; BDBM50388879; AKOS009158950
EINECS	Contact for details

Quality Control

Our high-purity pharmaceutical intermediate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.