Description

2-Fluoro-3-Iodo-4-Methylbenzaldehyde is a versatile halogenated benzaldehyde derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable precursor for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the reactivity of the aldehyde and halogen groups.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science: Employed in the creation of organic electronic materials, liquid crystals, and advanced polymers where halogenated aromatic units are required.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A high-value starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Fluoro-3-Iodo-4-Methylbenzaldehyde
CAS No.	909185-87-1
Molecular Formula	C8H6FIO
Molecular Weight	264.04 g/mol
Synonyms	3-Iodo-2-fluoro-4-methylbenzaldehyde; 4-Methyl-2-fluoro-3-iodobenzaldehyde; 2-Fluoro-3-iodo-p-tolualdehyde; Benzaldehyde, 2-fluoro-3-iodo-4-methyl-; 909185-87-1; AI3-31070; AKOS040759583; ZINC000068022735; SCHEMBL2182655
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-3-Iodo-4-Methylbenzaldehyde is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.