Description

4-Chloro-7H-Pyrrolo[2,3-d]pyrimidine-5-carbaldehyde is a high-purity, versatile heterocyclic building block of significant importance in modern organic synthesis. This compound serves as a critical intermediate for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by research institutions and industrial R&D departments focused on developing novel active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, anticancer agents, and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its reactive aldehyde and chloro-substituted heterocyclic core.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of chemical probes, enzyme inhibitors, and molecular tools for studying biological processes.
• Material Science: Serves as a building block for creating novel organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic semiconductors.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and advanced intermediates under cGMP conditions.

Basic Information

Product Name	4-Chloro-7H-Pyrrolo[2,3-d]pyrimidine-5-carbaldehyde
CAS No.	908287-21-8
Molecular Formula	C7H4ClN3O
Molecular Weight	181.58 g/mol
Synonyms	4-Chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carboxaldehyde; 5-Formyl-4-chloro-7H-pyrrolo[2,3-d]pyrimidine; 4-Chloro-5-formyl-7H-pyrrolo[2,3-d]pyrimidine; 908287-21-8; 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbaldehyde; 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine-5-aldehyde
EINECS	Contact for details

Quality Control

Our 4-Chloro-7H-Pyrrolo[2,3-d]pyrimidine-5-carbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.