Description

n-α-(9-Fluorenylmethyloxycarbonyl)-n-(4-Aminobutyl)-Glycine Hydrochloride is a specialized, high-purity amino acid derivative designed for advanced peptide synthesis and bioconjugation. This compound is critical for researchers and manufacturers requiring precise, site-specific modifications in complex molecular architectures. It is primarily utilized in the pharmaceutical, biotechnology, and life science research sectors for developing novel therapeutic peptides, diagnostic agents, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key building block for introducing a protected amino group with an extended linker arm, facilitating the synthesis of complex peptides and peptidomimetics.
• Bioconjugation and Linker Chemistry: Used to create stable amide bonds for attaching peptides, proteins, or other molecules to surfaces, carriers, or fluorescent labels.
• Pharmaceutical Intermediate: Acts as a crucial intermediate in the research and development of new active pharmaceutical ingredients (APIs), particularly in oncology and targeted drug delivery systems.
• Proteomics and Biochemical Research: Employed in the study of protein-protein interactions, enzyme mechanisms, and the development of affinity purification tags.
• Material Science Functionalization: Used to modify polymers, nanoparticles, and other materials with bioactive peptide sequences for biomedical applications.

Basic Information

Product Name	n-α-(9-Fluorenylmethyloxycarbonyl)-n-(4-Aminobutyl)-Glycine Hydrochloride
CAS No.	908117-93-1
Molecular Formula	C21H25ClN2O5
Molecular Weight	420.89 g/mol
Synonyms	Fmoc-4-Abu-Gly-OH·HCl; Fmoc-4-Aminobutyl-Gly-OH Hydrochloride; Nα-Fmoc-N4-(4-aminobutyl)glycine hydrochloride; N-(9-Fluorenylmethoxycarbonyl)-N'-(4-aminobutyl)glycine hydrochloride; Fmoc-Ahx-Gly-OH·HCl (Note: Ahx = 6-aminohexanoic acid/aminocaproic acid, a common but not identical analog); Glycine, N-[4-(aminobutyl)]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, hydrochloride (1:1); Fmoc protected aminobutyl glycine HCl
EINECS	Contact for details

Quality Control

Our n-α-(9-Fluorenylmethyloxycarbonyl)-n-(4-Aminobutyl)-Glycine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and specific tests for residual solvents and moisture content. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.