Description

5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidine-2,4(1H,3H)-Dione Hydrochloride is a high-purity pharmaceutical intermediate and building block with significant synthetic utility. This compound is valued for its role as a key precursor in the development of active pharmaceutical ingredients (APIs) and novel chemical entities. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug molecules, particularly those targeting neurological and oncological pathways.
• Organic Synthesis Reagent: Used in research laboratories for constructing fused pyrimidine ring systems, which are common scaffolds in medicinal chemistry.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development, validation, and quality control in API manufacturing.
• Biochemical Research: Employed in the study of enzyme inhibitors and receptor ligands due to its heterocyclic structure.
• Process Development: Used for scaling up synthetic routes and optimizing production processes for candidate drugs.

Basic Information

Product Name	5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidine-2,4(1H,3H)-Dione Hydrochloride
CAS No.	908010-94-6
Molecular Formula	C7H9N3O2·HCl
Molecular Weight	203.63 g/mol (Free base: 167.17 g/mol)
Synonyms	1,2,3,4-Tetrahydro-2,4-dioxopyrido[4,3-d]pyrimidine Hydrochloride; 5,6,7,8-Tetrahydropyrido[4,3-d]pyrimidine-2,4(1H,3H)-dione HCl; 2,4(1H,3H)-Pyrimidinedione, 5,6,7,8-tetrahydro-3H-pyrido[4,3-d]pyrimidine, hydrochloride; Tetrahydro-2,4-dioxopyrido[4,3-d]pyrimidine Hydrochloride; CAS 908010-94-6
EINECS	Contact for details

Quality Control

Our 5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidine-2,4(1H,3H)-Dione Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.