Description

Mpeg16-Nh2 CAS NO 907577-50-8 is a high-purity, monodisperse polyethylene glycol (PEG) derivative featuring a primary amine (-NH2) functional group at one terminus. This bifunctional molecule is critical for creating stable, biocompatible conjugates in advanced pharmaceutical and biotechnological applications. It is primarily utilized by researchers and manufacturers in drug delivery, bioconjugation, and surface modification who require precise linker chemistry and reliable, reproducible performance.

Application

• Bioconjugation Linker: Covalently links therapeutic proteins, peptides, or antibodies to drug payloads, nanoparticles, or solid surfaces.
• PEGylation Reagent: Used to modify biologics to enhance solubility, reduce immunogenicity, and prolong circulation half-life.
• Surface Functionalization: Amine-terminated PEG for creating non-fouling, hydrophilic coatings on medical devices, biosensors, and diagnostic platforms.
• Crosslinking Agent: Facilitates the formation of hydrogels and polymer networks for tissue engineering and controlled release systems.
• Nanoparticle Modification: Attaches to liposomes, polymeric nanoparticles, or quantum dots to provide active targeting sites for further ligand attachment.
• Diagnostic Probe Synthesis: Serves as a spacer arm for attaching fluorescent dyes, chelators, or other reporter molecules to targeting moieties.

Basic Information

Item	Details
Product Name	Mpeg16-Nh2
CAS No.	907577-50-8
Molecular Formula	C34H69NO17 (Typical for mPEG-NH2, 2000 Da)
Molecular Weight	~2000 g/mol (Contact for exact lot-specific value)
Synonyms	Methoxy PEG Amine (2000); mPEG2000-NH2; α-Methoxy-ω-amino poly(ethylene glycol); Poly(ethylene glycol) methyl ether amine; PEG Methyl Ether Amine; 2-Methoxyethylamine ethoxylate; O-Methylpolyethylene glycol amine; Amino-PEG-OMe
EINECS	Contact for details

Quality Control

Every batch of Mpeg16-Nh2 is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure it meets the high standards required for pharmaceutical and life science research. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data for purity, molecular weight distribution, and functional group content. Our quality commitment supports applications requiring GMP-grade materials and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C to -10°C under desiccant. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white waxy solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Molecular Weight (SEC-MALS)	1900 - 2100 Da
Dispersity (Đ)	≤ 1.05
Amine Value (Titration)	0.45 - 0.55 meq/g
Moisture (KF)	≤ 1.0 %
Residual Solvent (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.