Description

2-Bromo-5-Iodopyrimidine is a high-value halogenated pyrimidine building block essential for advanced organic synthesis. This compound is specifically engineered to serve as a versatile intermediate in the creation of complex molecules, offering precise reactivity for cross-coupling and functionalization reactions. It is a critical raw material for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-purity precursors for drug discovery and specialty chemical development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral and anticancer drug candidates.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides due to its reactive halogen sites.
• Material Science: Serves as a precursor for creating functionalized organic materials and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Nucleoside & Nucleotide Analog Synthesis: Employed in the modification of nucleosides for biochemical and therapeutic applications.
• Chemical Biology Probes: Used to create labeled compounds and probes for studying biological mechanisms.

Basic Information

Product Name	2-Bromo-5-Iodopyrimidine
CAS No.	905856-70-4
Molecular Formula	C4H2BrIN2
Molecular Weight	308.88 g/mol
Synonyms	5-Iodo-2-bromopyrimidine; 2-Bromo-5-iodo-pyrimidine; Pyrimidine, 2-bromo-5-iodo-; 905856-70-4; AI3-31255; SCHEMBL11827579; ZINC000005998961; AKOS005258890
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-Iodopyrimidine is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. Our standard grade meets specifications suitable for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.