Description

3-Fluoro-2-Iodobenzaldehyde is a versatile halogenated aromatic aldehyde building block of significant importance in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging the bioactivity of halogenated aromatic systems.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis, such as cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, including OLEDs and liquid crystals, where fluorine substitution enhances stability and performance.
• Chemical Biology Probes: Useful for creating fluorescent tags or molecular probes for studying biological processes due to its reactive aldehyde group.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings to build biaryl systems.

Basic Information

Product Name	3-Fluoro-2-Iodobenzaldehyde
CAS No.	905808-02-8
Molecular Formula	C7H4FIO
Molecular Weight	249.01 g/mol
Synonyms	2-Iodo-3-fluorobenzaldehyde; 3-Fluoro-2-iodobenzenecarboxaldehyde; 2-Fluoro-6-iodobenzaldehyde; 3-Fluoro-o-iodobenzaldehyde; Benzenecarboxaldehyde, 3-fluoro-2-iodo-; 3-Fluoro-2-iodo-benzaldehyde; 905808-02-8; 3-Fluoro-2-iodobenzaldehyde
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-Iodobenzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.