Description

1-(5-Fluoropyrimidin-2-yl)ethanone is a high-purity fluorinated pyrimidine derivative, a key building block in advanced organic synthesis. Its value lies in providing a reactive ketone functional group adjacent to a fluorinated heterocyclic core, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, including kinase inhibitors and antiviral agents.
• Agrochemical Research: Used to develop novel herbicides and pesticides with enhanced activity and selectivity.
• Material Science: Serves as a building block for creating specialty polymers and liquid crystals with unique electronic properties.
• Chemical Synthesis: Employed in cross-coupling reactions and as a versatile scaffold for constructing complex heterocyclic compounds in R&D.
• Bioconjugation & Probe Development: Utilized in the creation of fluorescent probes and biochemical tools for diagnostic applications.

Basic Information

Product Name	1-(5-Fluoropyrimidin-2-yl)ethanone
CAS No.	905587-44-2
Molecular Formula	C6H5FN2O
Molecular Weight	140.12 g/mol
Synonyms	2-Acetyl-5-fluoropyrimidine; 5-Fluoro-2-acetylpyrimidine; Ethanone, 1-(5-fluoro-2-pyrimidinyl)-; 1-(5-Fluoro-2-pyrimidinyl)ethanone; 5-Fluoropyrimidine-2-carbaldehyde (common misnomer); 5-Fluoro-2-pyrimidinyl methyl ketone; 2-Pyrimidinyl, 5-fluoro-, ethanone derivative
EINECS	Contact for details

Quality Control

Our 1-(5-Fluoropyrimidin-2-yl)ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.