Description

2-(Trifluoromethyl)-6,7-Dihydro-5H-Pyrrolo[3,4-D]Pyrimidine is a high-value, fluorinated heterocyclic building block essential for modern pharmaceutical and agrochemical research. Its unique pyrrolopyrimidine core, functionalized with a trifluoromethyl group, makes it a critical intermediate for introducing desirable pharmacokinetic properties into target molecules. This compound is primarily sought by medicinal chemists and process development scientists working in drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key scaffold in the synthesis of kinase inhibitors, anticancer agents, and other small molecule therapeutics.
• Agrochemical Research: Used in developing advanced herbicides, fungicides, and insecticides where the CF3 group enhances biological activity and metabolic stability.
• Material Science: Serves as a precursor for specialty polymers and advanced organic electronic materials.
• Chemical Biology: Employed as a probe or labeling agent in biochemical studies due to its distinctive fluorine signature.
• Academic & Contract Research: Utilized in universities and CROs for method development and novel heterocyclic chemistry exploration.

Basic Information

Product Name	2-(Trifluoromethyl)-6,7-Dihydro-5H-Pyrrolo[3,4-D]Pyrimidine
CAS No.	905274-04-6
Molecular Formula	C7H6F3N3
Molecular Weight	189.14 g/mol
Synonyms	2-(Trifluoromethyl)-5,6,7,8-tetrahydropyrrolo[3,4-d]pyrimidine; 6,7-Dihydro-5H-pyrrolo[3,4-d]pyrimidine, 2-(trifluoromethyl)-; 2-Trifluoromethyl-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine; Pyrrolo[3,4-d]pyrimidine, 6,7-dihydro-2-(trifluoromethyl)-5H-; 905274-04-6; 2-Trifluoromethyl-5,6,7,8-tetrahydropyrrolo[3,4-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)-6,7-Dihydro-5H-Pyrrolo[3,4-D]Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures material suitability for demanding R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.