Description

Ds(+)-Threo-Isocitric Acid . Trisodium Salt is a high-purity, biologically relevant salt form of isocitric acid, a key intermediate in the citric acid (Krebs) cycle. This compound is valued for its role as a chiral building block and biochemical reagent in advanced research and manufacturing processes. It is essential for pharmaceutical development, enzymatic studies, and the synthesis of fine chemicals where precise stereochemistry is critical.

Application

• Biochemical Research & Diagnostic Kits: As a critical substrate or standard in enzymatic assays for studying aconitase, isocitrate dehydrogenase, and other metabolic enzymes.
• Pharmaceutical Intermediate: Used in the synthesis of chiral active pharmaceutical ingredients (APIs) and complex molecules due to its defined stereochemistry.
• Cell Culture & Fermentation Media: Serves as a component in specialized culture media to study cellular metabolism and energy production pathways.
• Food & Beverage Analysis: Employed as an analytical reference standard for quantifying isocitric acid content in fruit juices, wines, and other food products for quality control.
• Cosmetic & Personal Care: Potential use in skincare formulations for its role in cellular energy metabolism and antioxidant properties.
• Academic & Industrial R&D: A fundamental reagent for metabolic pathway research, enzymology studies, and the development of new biocatalytic processes.

Basic Information

Product Name	Ds(+)-Threo-Isocitric Acid . Trisodium Salt
CAS No.	903507-52-8
Molecular Formula	C6H5Na3O7 • xH2O
Molecular Weight	Anhydrous: 258.07 g/mol
Synonyms	(1R,2S)-1-Hydroxy-1,2,3-propanetricarboxylic Acid Trisodium Salt; (+)-Threo-Ds-Isocitric Acid Trisodium Salt; Trisodium Ds-Isocitrate; Isocitric Acid Trisodium Salt; NSC 83624; Trisodium (1R,2S)-1,2,3-trihydroxy-1,2,3-propanetricarboxylate
EINECS	Contact for details

Quality Control

Our Ds(+)-Threo-Isocitric Acid . Trisodium Salt is manufactured under strict quality management systems. Each batch is tested to ensure high chemical purity, correct stereochemistry, and consistent performance. A comprehensive Certificate of Analysis (COA) is provided, detailing parameters such as assay (HPLC), optical rotation, water content, and residual solvents. We support compliance with relevant GMP and ISO guidelines for research and pharmaceutical-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	+15.0° to +18.0° (c=1 in H2O)
Water Content (KF)	≤ 5.0%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines
pH (5% solution)	7.0 - 9.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.