Description

Methyl 4-Chloroquinazoline-8-Carboxylate is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in the strategic positioning of reactive sites, making it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Building block for developing new herbicides, fungicides, and plant growth regulators.
• Material Science: Used in the research of organic electronic materials and advanced polymers.
• Chemical Synthesis: Serves as a versatile scaffold for medicinal chemistry and library synthesis in drug discovery programs.
• Academic & Contract Research: Critical reagent for methodological development and novel reaction studies in academic and CRO laboratories.

Basic Information

Product Name	Methyl 4-Chloroquinazoline-8-Carboxylate
CAS No.	903130-01-8
Molecular Formula	C10H7ClN2O2
Molecular Weight	222.63 g/mol
Synonyms	Methyl 4-chloro-8-quinazolinecarboxylate; 8-Quinazolinecarboxylic acid, 4-chloro-, methyl ester; 4-Chloroquinazoline-8-carboxylic acid methyl ester; Methyl 4-chloroquinoline-8-carboxylate (common misnomer); 4-Chloro-8-quinazolinecarboxylic acid methyl ester; 903130-01-8; Methyl 4-Cl-quinazoline-8-COOMe
EINECS	Contact for details

Quality Control

Our Methyl 4-Chloroquinazoline-8-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to confirm identity and purity. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.