Description

(9H-Fluoren-9-Yl)Methyl 2,4-Dichloro-5H-Pyrrolo[3,4-D]Pyrimidine-6(7H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate designed for critical synthesis pathways. This compound is a key building block in the development of novel active pharmaceutical ingredients (APIs), particularly in the fields of oncology and antiviral research. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the synthesis of complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of targeted therapeutic agents, especially kinase inhibitors and other small-molecule drugs.
• Oncology Drug Research: Serves as a core scaffold for developing novel compounds that target specific cancer pathways.
• Antiviral Agent Development: Used in research programs aimed at creating new treatments for viral infections.
• Chemical Biology & Proteomics: Acts as a specialized reagent for probing enzyme activity and protein function in biochemical assays.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and pilot-scale production of candidate drugs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke molecules under cGMP or research-grade conditions.

Basic Information

Item	Details
Product Name	(9H-Fluoren-9-Yl)Methyl 2,4-Dichloro-5H-Pyrrolo[3,4-D]Pyrimidine-6(7H)-Carboxylate
CAS No.	903129-86-2
Molecular Formula	C21H15Cl2N3O2
Molecular Weight	412.27 g/mol
Synonyms	Fmoc-2,4-Dichloro-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidine-6-carboxylate; 2,4-Dichloro-6-(((9H-fluoren-9-yl)methoxy)carbonyl)-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidine; 6-(((9H-Fluoren-9-yl)methoxy)carbonyl)-2,4-dichloro-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidine; Fmoc-Dichloropyrrolopyrimidine; 2,4-Dichloro-6-Fmoc-5,6,7,8-tetrahydropyrrolo[3,4-d]pyrimidine; (9-Fluorenylmethyl) 2,4-dichloro-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidine-6-carboxylate
EINECS	Contact for details

Quality Control

Our (9H-Fluoren-9-Yl)Methyl 2,4-Dichloro-5H-Pyrrolo[3,4-D]Pyrimidine-6(7H)-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can be aligned with cGMP guidelines for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity. Keep the container tightly sealed in a desiccated environment after opening.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.