Description

2-(Methylthio)Pyrido[4,3-D]Pyrimidin-5(6H)-One is a high-value heterocyclic organic compound featuring a fused pyrido[4,3-d]pyrimidine core, distinguished by a methylthio substituent at the 2-position. This specific molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D and production teams in the pharmaceutical and biotechnology sectors for the synthesis of novel drug candidates, particularly in oncology and antiviral therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex active pharmaceutical ingredients (APIs) targeting specific biological pathways.
• Medicinal Chemistry Research: Serves as a core scaffold for designing and optimizing new chemical entities in drug discovery programs.
• Kinase Inhibitor Development: Used in the research and production of kinase inhibitors, a major class of therapeutics for cancer and inflammatory diseases.
• Chemical Biology Probes: Employed in the development of tool compounds for studying enzyme function and cellular signaling mechanisms.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clients.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	2-(Methylthio)Pyrido[4,3-D]Pyrimidin-5(6H)-One
CAS No.	902576-09-4
Molecular Formula	C8H7N3OS
Molecular Weight	193.23 g/mol
Synonyms	2-(Methylthio)-5,6-dihydropyrido[4,3-d]pyrimidin-5-one; 2-(Methylsulfanyl)-6H-pyrido[4,3-d]pyrimidin-5-one; 2-Methylsulfanyl-5,6-dihydro-pyrido[4,3-d]pyrimidin-5-one; 5(6H)-Pyrido[4,3-d]pyrimidinone, 2-(methylthio)-; 2-Methylmercapto-5,6-dihydropyrido[4,3-d]pyrimidin-5-one; CAS 902576-09-4
EINECS	Contact for details

Quality Control

Our 2-(Methylthio)Pyrido[4,3-D]Pyrimidin-5(6H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically by HPLC), and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.