Description

Boc-Albizziin is a protected amino acid derivative, specifically the tert-butoxycarbonyl (Boc) derivative of the non-proteinogenic amino acid L-2-amino-3-ureidopropanoic acid (Albizzin). This compound is a critical building block in solid-phase peptide synthesis (SPPS), where it serves to introduce the Albizzin moiety while protecting the amine functionality from unwanted side reactions. It is primarily utilized by research scientists and process chemists in pharmaceutical R&D and biotechnology for the synthesis of novel peptides, peptidomimetics, and enzyme inhibitors. The high purity and consistent quality of this intermediate are essential for ensuring the success and reproducibility of complex synthetic sequences.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key protected amino acid for the automated or manual assembly of peptide chains containing the Albizzin residue.
• Pharmaceutical Research & Development: For the discovery and synthesis of novel therapeutic peptides targeting specific enzymes or receptors.
• Bioconjugation & Probe Development: Used to create labeled peptides or peptide-based probes for biochemical and cellular studies.
• Enzyme Inhibitor Design: Incorporation into peptide scaffolds to develop potent and selective inhibitors for proteases and other enzymes.
• Combinatorial Chemistry Libraries: Serves as a building block in the generation of diverse peptide libraries for high-throughput screening.
• Academic Research: Fundamental studies in peptide chemistry, structure-activity relationships (SAR), and medicinal chemistry.

Basic Information

Product Name	Boc-Albizziin
CAS No.	901284-69-3
Molecular Formula	C9H17N3O5
Molecular Weight	247.25 g/mol
Synonyms	(S)-2-((tert-Butoxycarbonyl)amino)-3-ureidopropanoic acid; Boc-L-Albizzin; Nα-Boc-L-2-amino-3-ureidopropanoic acid; Nα-Boc-L-Albizzin; Boc-Albizzine; tert-Butyl (1-((S)-1-carboxy-2-ureidoethyl)carbamate); Albizzin, N-Boc-; L-2-Amino-3-ureidopropionic acid N-Boc derivative
EINECS	Contact for details

Quality Control

Our Boc-Albizziin is manufactured under strict quality control protocols to ensure high chemical purity and batch-to-batch consistency, suitable for demanding synthetic applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.