Description

3-Fluoro-2-Trifluoromethylphenol is a high-value fluorinated phenolic compound, serving as a critical building block in advanced chemical synthesis. Its unique structure, featuring both fluorine and trifluoromethyl substituents, imparts significant lipophilicity and metabolic stability to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing next-generation active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in CNS and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine motifs enhance biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance display technologies.
• Polymer Modification: Employed to introduce fluorine-containing phenolic groups into polymer chains, improving chemical resistance and surface properties.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions and nucleophilic aromatic substitutions to construct complex fluorinated aromatic systems.
• Research & Development: A valuable reagent for medicinal chemistry and material science research in academic and industrial laboratories.

Basic Information

Product Name	3-Fluoro-2-Trifluoromethylphenol
CAS No.	900512-27-8
Molecular Formula	C7H4F4O
Molecular Weight	180.10 g/mol
Synonyms	2-(Trifluoromethyl)-3-fluorophenol; 3-Fluoro-α,α,α-trifluoro-o-cresol; 3-Fluoro-2-(trifluoromethyl)phenol; 2-Hydroxy-6-fluorobenzotrifluoride; 3-Fluoro-α,α,α-trifluoro-2-cresol; Phenol, 3-fluoro-2-(trifluoromethyl)-; 3-Fluoro-2-trifluoromethyl-phenol
EINECS	Contact for details

Quality Control

Our production of 3-Fluoro-2-Trifluoromethylphenol adheres to stringent quality management protocols. Each batch is analytically verified to ensure high purity and consistency, meeting the exacting standards required for pharmaceutical and specialty chemical applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.