Description

4-Fluoro-5-Iodo-2-Methylphenol is a halogenated phenolic compound of significant interest in advanced organic synthesis. This specialty chemical serves as a versatile and critical building block for the development of complex molecular architectures, particularly in pharmaceutical and agrochemical research. Its unique substitution pattern makes it a valuable precursor for medicinal chemists and R&D professionals seeking to introduce specific fluorine and iodine functionalities into target molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides, where the fluorine and iodine atoms can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis and in materials science research.
• Fluorinated Compound Library: An essential reagent for constructing diverse fluorinated compound libraries for high-throughput screening in drug discovery programs.
• Chemical Biology Probes: Useful in the design of molecular probes and tags for studying biological processes, leveraging the iodine atom for potential radiolabeling (e.g., with I-125).
• Advanced Material Precursor: Acts as a monomer or functionalization agent in the synthesis of specialty polymers and advanced organic electronic materials.

Basic Information

Item	Detail
Product Name	4-Fluoro-5-Iodo-2-Methylphenol
CAS No.	900175-53-3
Molecular Formula	C7H6FIO
Molecular Weight	252.03 g/mol
Synonyms	2-Methyl-4-fluoro-5-iodophenol; 5-Iodo-4-fluoro-2-methylphenol; 4-Fluoro-5-iodo-o-cresol; 2-Hydroxy-5-iodo-4-fluorotoluene; 5-Iodo-4-fluoro-2-methyl-hydroxybenzene; 4-Fluoro-5-iodo-2-cresol; Phenol, 4-fluoro-5-iodo-2-methyl-
EINECS	Contact for details

Quality Control

Every batch of 4-Fluoro-5-Iodo-2-Methylphenol is manufactured and tested under a strict quality management system. We ensure compliance with high-purity standards suitable for research and development applications. Comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or kept in secondary opaque packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.