Description

2-Chloro-5-Methoxy-Pyrimidin-4-Ylamine is a high-purity pyrimidine derivative building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated methoxy-pyrimidine structure enables precise molecular modifications. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in antiviral, anticancer, and kinase inhibitor research.
• Agrochemical Active Ingredient Development: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Chemical Synthesis Building Block: Employed in organic synthesis for constructing complex heterocyclic compounds and fine chemicals.
• Material Science Research: Investigated as a precursor for the development of advanced organic electronic materials and ligands for catalysis.
• Biochemical Research: Utilized in life science research as a molecular probe or for modifying nucleoside analogs.

Basic Information

Product Name	2-Chloro-5-Methoxy-Pyrimidin-4-Ylamine
CAS No.	99979-77-8
Molecular Formula	C5H6ClN3O
Molecular Weight	159.57 g/mol
Synonyms	4-Amino-2-chloro-5-methoxypyrimidine; 2-Chloro-5-methoxy-4-pyrimidinamine; 2-Chloro-5-methoxypyrimidin-4-amine; 5-Methoxy-2-chloro-4-pyrimidinamine; 4-Pyrimidinamine, 2-chloro-5-methoxy-; 2-Chloro-5-methoxy-4-aminopyrimidine; 2-Chloro-5-methoxypyrimidine-4-amine
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Methoxy-Pyrimidin-4-Ylamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, and NMR for comprehensive characterization and impurity profiling. Certificates of Analysis (COA) detailing purity, identity, and specific tests are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.