Description

4,6-Dichloro-1-Phenyl-1H-Pyrazolo[3,4-D]Pyrimidine is a high-value heterocyclic organic compound serving as a critical synthetic intermediate. Its core value lies in its versatile pyrazolo[3,4-d]pyrimidine scaffold, which is a privileged structure in medicinal chemistry for designing potent bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly those focused on developing kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel kinase inhibitors (e.g., JAK, Src family kinases) and other small-molecule drug candidates.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its heterocyclic core for bioactivity.
• Chemical Biology Probe: Serves as a core scaffold for creating tool compounds to study specific enzyme functions and signaling pathways.
• Organic Synthesis: A versatile precursor for further functionalization via cross-coupling, nucleophilic substitution, and other reactions to create diverse chemical libraries.
• Material Science Research: Potential intermediate for the synthesis of organic electronic materials and ligands for metal-organic frameworks (MOFs).

Basic Information

Product Name	4,6-Dichloro-1-Phenyl-1H-Pyrazolo[3,4-D]Pyrimidine
CAS No.	99971-84-3
Molecular Formula	C11H6Cl2N4
Molecular Weight	265.10 g/mol
Synonyms	1H-Pyrazolo[3,4-d]pyrimidine, 4,6-dichloro-1-phenyl-; 4,6-Dichloro-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine; 1-Phenyl-4,6-dichloro-1H-pyrazolo[3,4-d]pyrimidine; 4,6-Dichloro-1-phenylpyrazolo[3,4-d]pyrimidine; PP1 Analog; Pyrazolopyrimidine Derivative; Kinase Inhibitor Intermediate
EINECS	Contact for details

Quality Control

Our 4,6-Dichloro-1-Phenyl-1H-Pyrazolo[3,4-D]Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications to support your R&D and cGMP manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.