Description

2-Ethoxy-5-Nitro-3H-Pyrimidin-4-One is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, where its unique pyrimidinone core offers versatile functionalization points. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in antiviral, anticancer, and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and other performance chemicals requiring a nitro-substituted pyrimidine scaffold.
• Academic & Industrial Research: Employed in medicinal chemistry programs and material science for creating new molecular libraries.
• Chemical Biology Probes: Useful for synthesizing labeled compounds or probes for studying biological mechanisms.

Basic Information

Product Name	2-Ethoxy-5-Nitro-3H-Pyrimidin-4-One
CAS No.	99968-75-9
Molecular Formula	C6H7N3O4
Molecular Weight	185.14 g/mol
Synonyms	5-Nitro-2-ethoxy-3H-pyrimidin-4-one; 2-Ethoxy-5-nitropyrimidin-4(3H)-one; 4(3H)-Pyrimidinone, 2-ethoxy-5-nitro-; 5-Nitro-2-ethoxy-4-pyrimidinol; 2-Ethoxy-5-nitro-4-pyrimidinol; 5-Nitro-2-ethoxy-4(3H)-pyrimidinone; 99968-75-9
EINECS	Contact for details

Quality Control

Our 2-Ethoxy-5-Nitro-3H-Pyrimidin-4-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical and fine chemical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.