Description

L-Tyrosine, N[(1,1-Dimethylethoxy) Carbonyl] -2,6 is a protected derivative of the essential amino acid L-Tyrosine, specifically designed for advanced peptide synthesis and pharmaceutical research. This compound is critical for researchers and manufacturers who require precise control over amino acid side-chain reactivity during complex multi-step synthetic processes. It is primarily utilized in the development of peptide-based therapeutics, active pharmaceutical ingredients (APIs), and as a key building block in medicinal chemistry.

Application

• Peptide Synthesis: Serves as a crucial protected intermediate in solid-phase and solution-phase peptide synthesis (SPPS), preventing unwanted side reactions at the tyrosine hydroxyl group.
• Pharmaceutical Research: Used as a building block for the research and development of novel peptide hormones, enzyme inhibitors, and other bioactive molecules.
• API Manufacturing: Employed in the scalable production of Active Pharmaceutical Ingredients (APIs) that contain tyrosine residues, ensuring high purity and yield.
• Medicinal Chemistry: Facilitates the exploration of structure-activity relationships (SAR) by allowing selective deprotection and further functionalization.
• Bioconjugation: Acts as a starting material for creating labeled peptides or peptide-drug conjugates for diagnostic and therapeutic applications.

Basic Information

Product Name	L-Tyrosine, N[(1,1-Dimethylethoxy) Carbonyl] -2,6
CAS No.	99953-00-1
Molecular Formula	C14H19NO5
Molecular Weight	281.30 g/mol
Synonyms	Boc-Tyr(2,6-Di-Cl-Bzl)-OH; N-Boc-O-(2,6-Dichlorobenzyl)-L-tyrosine; N-tert-Butoxycarbonyl-O-(2,6-dichlorobenzyl)-L-tyrosine; Boc-L-Tyrosine(2,6-Di-Cl-Bzl)-OH; (2S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-[4-[(2,6-dichlorophenyl)methoxy]phenyl]propanoic acid; Boc-Tyr(2,6-DCl-Bzl)-OH; Boc-O-(2,6-Dichlorobenzyl)-L-tyrosine
EINECS	Contact for details

Quality Control

Our L-Tyrosine, N[(1,1-Dimethylethoxy) Carbonyl] -2,6 is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical research and peptide synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	-15.0° to -20.0° (c=1 in DMF)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.