Description

Ethyl 5-Chloro[1,2,4]Triazolo[4,3-A]Pyrimidine-7-Carboxylate is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound matters for its critical role in the synthesis of complex molecules, particularly in medicinal chemistry and agrochemical research. Pharmaceutical R&D teams, agrochemical manufacturers, and fine chemical producers need it to develop new active ingredients, leveraging its fused triazolopyrimidine core structure for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or insecticides, where the triazolopyrimidine scaffold can confer specific biological activity.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for creating chemical probes and tool compounds to study enzyme function and biological pathways.
• Material Science Research: Investigated as a building block for specialty polymers or organic electronic materials due to its electron-deficient aromatic system.
• Academic & Contract Research: Essential for synthetic organic chemistry research in universities and CROs (Contract Research Organizations) exploring new heterocyclic methodologies.
• Custom Synthesis: A starting material for the contract manufacturing of bespoke, high-value fine chemicals for client-specific projects.

Basic Information

Product Name	Ethyl 5-Chloro[1,2,4]Triazolo[4,3-A]Pyrimidine-7-Carboxylate
CAS No.	99951-90-3
Molecular Formula	C8H7ClN4O2
Molecular Weight	226.62 g/mol
Synonyms	5-Chloro[1,2,4]triazolo[4,3-a]pyrimidine-7-carboxylic acid ethyl ester; Ethyl 5-chloro-1,2,4-triazolo[4,3-a]pyrimidine-7-carboxylate; 7-Carbethoxy-5-chloro[1,2,4]triazolo[4,3-a]pyrimidine; 5-Chloro-7-(ethoxycarbonyl)-[1,2,4]triazolo[4,3-a]pyrimidine; 99951-90-3; [1,2,4]Triazolo[4,3-a]pyrimidine-7-carboxylic acid, 5-chloro-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-Chloro[1,2,4]Triazolo[4,3-A]Pyrimidine-7-Carboxylate is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Handle and store in accordance with all applicable local and international regulations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.