Description

n-Formylmethionine-Thioamide-Leucyl-Phenylalanine Methyl Ester is a specialized synthetic peptide derivative, primarily utilized as a key intermediate in advanced pharmaceutical research and development. Its value lies in its role as a building block for synthesizing more complex peptide structures and for studying biochemical pathways. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors, particularly those focused on protease research, drug discovery, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for investigating protease and peptidase activity and mechanisms.
• Protease Inhibitor Development: Serves as a core structure or precursor in the design and screening of novel protease inhibitors for therapeutic applications.
• Peptide Library Synthesis: Employed in combinatorial chemistry and solid-phase peptide synthesis to create diverse libraries for high-throughput screening.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting fundamental research in biochemistry and medicinal chemistry.
• Reference Standard: Can be used as a certified reference material (CRM) for analytical method development and validation in quality control laboratories.

Basic Information

Product Name	n-Formylmethionine-Thioamide-Leucyl-Phenylalanine Methyl Ester
CAS No.	99929-11-0
Molecular Formula	C23H34N4O5S
Molecular Weight	478.61 g/mol
Synonyms	N-Formyl-Met-Thioamide-Leu-Phe-OMe; For-Metψ[CS-NH]-Leu-Phe-OMe; Formylmethionyl Thioamidoleucyl Phenylalanine Methyl Ester; N-Formyl-L-methionyl-L-leucyl-L-phenylalanine Methyl Ester Thioamide Analogue; Peptide Inhibitor Intermediate; CAS 99929-11-0; FMLF Methyl Ester Thioamide
EINECS	Contact for details

Quality Control

Our n-Formylmethionine-Thioamide-Leucyl-Phenylalanine Methyl Ester is produced under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for demanding research applications. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.