Description

Glycyl-Arginyl-Glycyl-Glutamyl-Seryl-Proline is a synthetic hexapeptide with the sequence GRGESP. This compound is of significant interest in biochemical and pharmaceutical research due to its role as a specific ligand and inhibitor for certain integrin receptors. It is primarily utilized by research institutions and biotechnology companies focused on cell adhesion studies, cancer research, and the development of novel therapeutic agents targeting integrin-mediated pathways.

Application

• Biochemical Research: Used as a tool compound to study integrin receptor function and signaling pathways.
• Cell Adhesion Studies: Serves as a specific substrate or competitive inhibitor in assays investigating cell-matrix interactions.
• Cancer Research: Investigated for its potential to modulate tumor cell migration, invasion, and angiogenesis.
• Pharmaceutical Development: A candidate starting material or reference standard in the discovery of anti-thrombotic or anti-metastatic drugs.
• Diagnostic Reagent Formulation: Potential component in diagnostic kits designed to detect or quantify specific integrin activity.

Basic Information

Product Name	Glycyl-Arginyl-Glycyl-Glutamyl-Seryl-Proline
CAS No.	99896-88-5
Molecular Formula	C26H45N11O11
Molecular Weight	663.70 g/mol
Synonyms	GRGESP Peptide; GRGESP; H-Gly-Arg-Gly-Glu-Ser-Pro-OH; Integrin α5β1 Ligand Peptide; Fibronectin Fragment Peptide; (Glycyl-L-arginylglycyl-L-α-glutamyl-L-seryl-L-proline); L-Glycyl-L-arginylglycyl-L-α-glutamyl-L-seryl-L-proline
EINECS	Contact for details

Quality Control

Our peptide products are manufactured under strict quality management systems. Each batch of Glycyl-Arginyl-Glycyl-Glutamyl-Seryl-Proline is subjected to comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing all specification parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC & MS)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Amino Acid Analysis	Within ± 10% of theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.