Description

Arg-Gly-Asp CAS NO 99896-85-2 is a synthetic tripeptide composed of the amino acids L-Arginine, Glycine, and L-Aspartic acid, widely recognized as the RGD sequence. This sequence is a critical cell adhesion motif that mediates interactions with integrin receptors, making it a fundamental tool in biochemical and biomedical research. It is essential for researchers and manufacturers in the fields of cell biology, tissue engineering, and drug discovery who require high-purity peptides to study cellular adhesion, signaling, and biomaterial development.

Application

• Biomedical Research: As a key ligand for studying integrin-mediated cell adhesion, migration, and signaling pathways in vitro.
• Tissue Engineering & Biomaterials: Coating or incorporating into scaffolds (e.g., hydrogels, polymers) to promote specific cell attachment and tissue regeneration.
• Drug Discovery & Development: Serving as a lead compound or targeting moiety for designing novel therapeutics, including anti-angiogenic and anti-thrombotic agents.
• Diagnostic Assays: Used in assay development to screen for integrin inhibitors or to study receptor-ligand interactions.
• Cell Culture: Functionalizing surfaces to create defined microenvironments for controlled cell culture studies.
• Bioconjugation: Acting as a linker or active targeting group for nanoparticle and drug delivery system functionalization.

Basic Information

Product Name	Arg-Gly-Asp
CAS No.	99896-85-2
Molecular Formula	C14H26N8O6
Molecular Weight	402.41 g/mol
Synonyms	RGD Peptide; Arg-Gly-Asp-OH; H-Arg-Gly-Asp-OH; L-Arginylglycyl-L-aspartic acid; Adhesion Motif Peptide; Cyclo(RGDfK); RGDS; GRGDSP; ATCG (amino acid code); Integrin Binding Peptide; Cell Adhesion Peptide
EINECS	Contact for details

Quality Control

Our Arg-Gly-Asp is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, solvent content, and other critical parameters are provided to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Assay (Amino Acid Analysis)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.