Description

Pyr-Leu-Thr-Phe-Thr-Ser-Ser-Trp-Gly-Nh2 is a synthetic nonapeptide amide, a sequence of nine amino acids with a pyroglutamyl (Pyr) N-terminus and a C-terminal amide. This compound is of significant interest in biochemical and pharmaceutical research due to its specific peptide structure, which can be utilized as a reference standard, a building block for larger peptides, or a tool for studying biological interactions. It is primarily required by research institutions, biotechnology companies, and pharmaceutical developers engaged in peptide synthesis, proteomics, and drug discovery programs.

Application

• Biochemical Research: Used as a reference standard or substrate in enzymatic studies and protein interaction assays.
• Pharmaceutical R&D: Serves as a key intermediate or a model compound in the development of novel peptide-based therapeutics.
• Proteomics & Mass Spectrometry: Employed as a calibration standard or a spike-in control for peptide analysis and quantification.
• Peptide Library Synthesis: Acts as a building block or a core sequence in the combinatorial synthesis of peptide libraries for screening.
• Academic Studies: Utilized in university laboratories for teaching advanced peptide chemistry and structure-activity relationship (SAR) studies.
• Antibody Production: Can be conjugated to carrier proteins for the generation of sequence-specific antibodies.

Basic Information

Product Name	Pyr-Leu-Thr-Phe-Thr-Ser-Ser-Trp-Gly-Nh2
CAS No.	99886-31-4
Molecular Formula	C53H71N11O14
Molecular Weight	1086.21 g/mol
Synonyms	Pyroglutamyl-Leucyl-Threonyl-Phenylalanyl-Threonyl-Seryl-Seryl-Tryptophyl-Glycinamide; pGlu-Leu-Thr-Phe-Thr-Ser-Ser-Trp-Gly-NH2; Pyr-Leu-Thr-Phe-Thr-Ser-Ser-Trp-Gly-NH2; Nonapeptide amide (pGlu-Leu-Thr-Phe-Thr-Ser-Ser-Trp-Gly-NH2); L-Pyroglutamyl-L-leucyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-seryl-L-tryptophylglycinamide
EINECS	Contact for details

Quality Control

Our peptide products are manufactured under strict quality management systems. Each batch of Pyr-Leu-Thr-Phe-Thr-Ser-Ser-Trp-Gly-Nh2 undergoes rigorous analytical testing, including HPLC for purity and MS for identity confirmation, to ensure compliance with research-grade specifications. Certificates of Analysis (COA) detailing purity, chromatographic data, and batch-specific information are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. For long-term storage, consider lyophilized powder under inert atmosphere. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC & MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Solubility	Soluble in DMSO, Acetic Acid; Slightly soluble in Water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.