Description

1-(4-Bromophenyl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine is a high-purity, advanced pharmaceutical intermediate and research chemical. This compound is a key synthetic building block valued for its role in the development of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors and other targeted small-molecule drugs.
• Biochemical Research: Used as a reference standard and active probe in enzymatic and cellular assays to study biological pathways.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization programs.
• Process Development: Employed in scaling up synthetic routes for Active Pharmaceutical Ingredient (API) manufacturing under cGMP conditions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and early-stage clinical material production.

Basic Information

Product Name	1-(4-Bromophenyl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine
CAS No.	99867-27-3
Molecular Formula	C11H8BrN5
Molecular Weight	290.12 g/mol
Synonyms	4-Amino-1-(4-bromophenyl)-1H-pyrazolo[3,4-d]pyrimidine; 1-(4-Bromophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 99867-27-3; 4-Amino-1-(p-bromophenyl)pyrazolo[3,4-d]pyrimidine; 1-(p-Bromophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; BPPA; 4-Amino-1-(4'-bromophenyl)pyrazolo[3,4-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 1-(4-Bromophenyl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.