Description

1-Ethyl-7-[(3S)-3-[(Ethylamino)Methyl]-1-Pyrrolidinyl]-6,8-Difluoro-1,4-Dihydro-4-Oxo-3-Quinolinecarboxylic Acid is a high-purity synthetic intermediate of significant importance in advanced pharmaceutical research and development. This compound serves as a critical building block in the synthesis of novel fluoroquinolone antibiotics, a class known for their broad-spectrum antibacterial activity. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents and producing reference standards.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of advanced fluoroquinolone antibiotic candidates.
• Active Pharmaceutical Ingredient (API) Development: Used in research for the development and structural optimization of new antibacterial agents.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Biochemical Research: Employed in studies investigating the structure-activity relationships (SAR) of quinolone-based compounds.
• Process Chemistry: Utilized in scaling up and optimizing synthetic routes for complex pharmaceutical molecules.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	1-Ethyl-7-[(3S)-3-[(Ethylamino)Methyl]-1-Pyrrolidinyl]-6,8-Difluoro-1,4-Dihydro-4-Oxo-3-Quinolinecarboxylic Acid
CAS No.	99735-05-4
Molecular Formula	C20H24F2N4O3
Molecular Weight	406.43 g/mol
Synonyms	1-Ethyl-6,8-difluoro-1,4-dihydro-7-[(3S)-3-[(ethylamino)methyl]-1-pyrrolidinyl]-4-oxo-3-quinolinecarboxylic acid; (S)-1-Ethyl-7-(3-((ethylamino)methyl)pyrrolidin-1-yl)-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; A fluoroquinolone intermediate; PD 117596; PD-117596; 3-Quinolinecarboxylic acid, 1,4-dihydro-1-ethyl-6,8-difluoro-7-[(3S)-3-[(ethylamino)methyl]-1-pyrrolidinyl]-4-oxo-; 99735-05-4
EINECS	Contact for details

Quality Control

Our 1-Ethyl-7-[(3S)-3-[(Ethylamino)Methyl]-1-Pyrrolidinyl]-6,8-Difluoro-1,4-Dihydro-4-Oxo-3-Quinolinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity verification, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (S-isomer)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.