Description

5-Fluoro-3-Acetylindole is a versatile and high-value fluorinated indole derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both an acetyl group and a fluorine atom on the indole scaffold, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly for central nervous system (CNS) agents, kinase inhibitors, and anti-cancer compounds.
• Agrochemical Research: Used in developing new-generation pesticides and herbicides where the fluorine atom enhances biological activity and environmental stability.
• Material Science: Serves as a monomer or functional unit in the creation of specialty polymers, organic semiconductors, and fluorescent dyes.
• Academic & R&D: Employed in medicinal chemistry and organic synthesis research for structure-activity relationship (SAR) studies and library synthesis.
• Bioconjugation Chemistry: The acetyl group provides a handle for further chemical modifications, useful in probe and linker molecule development.

Basic Information

Product Name	5-Fluoro-3-Acetylindole
CAS No.	99532-53-3
Molecular Formula	C10H8FNO
Molecular Weight	177.18 g/mol
Synonyms	1-(5-Fluoro-1H-indol-3-yl)ethanone; 3-Acetyl-5-fluoroindole; 5-Fluoro-3-indolyl methyl ketone; 5-Fluoroindole-3-yl methyl ketone; 5-Fluoro-1H-indole-3-acetyl; Ethanone, 1-(5-fluoro-1H-indol-3-yl)-
EINECS	Contact for details

Quality Control

Our 5-Fluoro-3-Acetylindole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, and we support our clients' regulatory needs for pharmaceutical and advanced material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.