Description

Pyrimidine, 5-Chloro-2-Fluoro-4-Methyl- (9Ci) is a halogenated pyrimidine derivative, a versatile and high-value organic building block. This compound is critical for the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the pyrimidine core provides specific biological activity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in organometallic chemistry and catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology & Proteomics: Acts as a molecular scaffold or a tagging reagent in probe development for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Pyrimidine, 5-Chloro-2-Fluoro-4-Methyl- (9Ci)
CAS No.	99429-16-0
Molecular Formula	C5H4ClFN2
Molecular Weight	146.55 g/mol
Synonyms	5-Chloro-2-fluoro-4-methylpyrimidine; 2-Fluoro-5-chloro-4-methylpyrimidine; 4-Methyl-5-chloro-2-fluoropyrimidine; 99429-16-0; 5-Chloro-2-fluoro-4-methyl-pyrimidine; Pyrimidine, 5-chloro-2-fluoro-4-methyl-; 2-Fluoro-4-methyl-5-chloropyrimidine
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-fluoro-4-methylpyrimidine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.