Description

2-Pyrimidinecarboxylic Acid, 5-Methyl- (6Ci,9Ci) CAS NO 99420-75-4 is a high-purity heterocyclic carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with pyrimidine cores, which are prevalent in active pharmaceutical ingredients and agrochemicals. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality intermediates for their synthesis pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, antiviral agents, and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and plant growth regulators that incorporate a substituted pyrimidine moiety.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, such as electron-transport layers or organic semiconductors.
• Chemical Biology Probes: Utilized to synthesize molecular probes for studying enzyme function and biological pathways involving pyrimidine metabolism.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up manufacturing under cGMP conditions for clinical trial materials.

Basic Information

Product Name	2-Pyrimidinecarboxylic Acid, 5-Methyl- (6Ci,9Ci) CAS NO 99420-75-4
CAS No.	99420-75-4
Molecular Formula	C6H6N2O2
Molecular Weight	138.12 g/mol
Synonyms	5-Methylpyrimidine-2-carboxylic acid; 5-Methyl-2-pyrimidinecarboxylic acid; 5-Methyl-2-pyrimidine carboxylic acid; 2-Carboxy-5-methylpyrimidine; 5-Methylpyrimidine-2-carboxylate; 99420-75-4; 5-Methyl-2-pyrimidinecarboxylate
EINECS	Contact for details

Quality Control

Our 2-Pyrimidinecarboxylic Acid, 5-Methyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.