Description

3-Bromo-D-Phenylalanine is a non-natural, chiral amino acid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a crucial chiral building block for the development of novel peptide-based therapeutics and enzyme inhibitors. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, particularly for creating targeted molecules with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially protease inhibitors and peptide drugs.
• Peptide Synthesis: Used to incorporate brominated phenylalanine residues into custom peptides to study structure-activity relationships (SAR) and modulate peptide properties.
• Biochemical Research: Acts as a substrate analog or inhibitor in enzymatic studies to investigate enzyme mechanisms and binding sites.
• Proteomics & Labeling: Potential use in the synthesis of affinity probes or photoaffinity labels for protein target identification and characterization.
• Material Science: Can be employed in the synthesis of specialized polymers or functional materials where chiral, aromatic motifs are required.

Basic Information

Product Name	3-Bromo-D-Phenylalanine
CAS No.	99295-78-0
Molecular Formula	C9H10BrNO2
Molecular Weight	244.09 g/mol
Synonyms	(R)-2-Amino-3-(3-bromophenyl)propanoic acid; D-3-Bromophenylalanine; (R)-3-Bromo-DL-phenylalanine; 3-Bromo-D-Phe; 3-Br-D-Phe-OH; 3-Bromophenylalanine, D-; β-(3-Bromophenyl)-D-alanine
EINECS	Contact for details

Quality Control

Our 3-Bromo-D-Phenylalanine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specific properties.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (D-Isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.