Description

L-Valine, n-Acetyl-L-Alanyl-, Methyl Ester (9Ci) is a protected dipeptide derivative, specifically an acetylated alanyl-valine methyl ester. This compound serves as a crucial building block and intermediate in advanced organic synthesis, offering controlled reactivity for constructing complex peptide structures. It is primarily utilized by pharmaceutical research and fine chemical synthesis laboratories focused on developing novel bioactive molecules and peptide-based therapeutics.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Chemistry Research: Used in solid-phase and solution-phase peptide synthesis (SPPS) to study structure-activity relationships.
• Bioconjugation: Serves as a linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Protecting Group Strategy: The acetyl and methyl ester groups provide orthogonal protection for peptide chain elongation in complex syntheses.
• Biochemical Tool Development: Utilized in creating enzyme substrates, inhibitors, or probes for biochemical and pharmacological assays.
• Fine Chemical Synthesis: Intermediate for the production of specialized chiral compounds and custom peptides for various industrial applications.

Basic Information

Product Name	L-Valine, n-Acetyl-L-Alanyl-, Methyl Ester (9Ci)
CAS No.	99141-91-0
Molecular Formula	C11H20N2O4
Molecular Weight	244.29 g/mol
Synonyms	N-Acetyl-L-alanyl-L-valine methyl ester; Ac-Ala-Val-OMe; Methyl N-acetyl-L-alanyl-L-valinate; L-Valine, N-acetyl-L-alanyl-, methyl ester; Acetylalanylvaline methyl ester; N-Acetylalanylvaline methyl ester; (2S)-2-[(2S)-2-Acetamidopropanamido]-3-methylbutanoic acid methyl ester; N-Acetyl-L-alanyl-L-valine methyl ester
EINECS	Contact for details

Quality Control

Our L-Valine, n-Acetyl-L-Alanyl-, Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring it meets the stringent requirements for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.