Description

n-ε-(2-Propenal)Lysine is a chemically modified amino acid derivative, specifically a lysine residue adducted with acrolein. This compound is of significant interest in biochemical and pharmaceutical research as a key biomarker for oxidative stress and lipid peroxidation. It serves as a critical reference standard and intermediate for scientists and manufacturers developing diagnostic assays and studying disease mechanisms related to cellular damage. Primary users include research institutions, diagnostic kit manufacturers, and pharmaceutical companies engaged in advanced proteomics and metabolomics.

Application

• Biomarker Research: Used as a precise reference standard in mass spectrometry and immunoassays to detect and quantify protein modifications caused by acrolein, a marker of oxidative stress.
• Diagnostic Development: Serves as a critical antigen or calibrator in the development of ELISA and other immunoassay kits for clinical diagnostics related to cardiovascular, neurodegenerative, and inflammatory diseases.
• Pharmaceutical R&D: Employed as a tool compound in drug discovery programs targeting pathways of oxidative damage and advanced glycation end-products (AGEs).
• Proteomic Studies: Essential for mapping and validating post-translational modifications on proteins in metabolic and toxicological studies.
• Reference Material Production: Used by certified reference material (CRM) producers to create characterized standards for quality control in clinical and research laboratories.

Basic Information

Product Name	n-ε-(2-Propenal)Lysine
CAS No.	99124-76-2
Molecular Formula	C9H16N2O3
Molecular Weight	200.24 g/mol
Synonyms	Nε-(3-Formyl-3,4-dehydropiperidino)lysine; Acrolein-Lysine Adduct; Nε-(2-Propenal)lysine; FDP-lysine; N6-(2-Propenal)-L-lysine; Lysine-acrolein adduct; 3-Formyl-3,4-dehydro- Nε-piperidinolysine
EINECS	Contact for details

Quality Control

Our n-ε-(2-Propenal)Lysine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the high standards required for research and diagnostic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.