Description

N(Alpha)-Acetyl-ε-(2-Propenal)Lysine is a specialized lysine derivative featuring both acetyl and propenal (acrolein) functional groups. This unique structure makes it a valuable intermediate for advanced biochemical research and pharmaceutical development, particularly in the study of protein modifications and advanced glycation end-products (AGEs). It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on metabolic disease research, aging studies, and the synthesis of novel bioactive compounds.

Application

• Biochemical Research Intermediate: A key building block for synthesizing more complex molecules used in metabolic pathway studies.
• AGEs (Advanced Glycation End-products) Research: Used as a standard or precursor in research models investigating diabetes, aging, and related pathologies.
• Pharmaceutical Development: Serves as a crucial intermediate in the R&D of potential therapeutic agents targeting metabolic disorders.
• Proteomics & Protein Chemistry: Employed in studies of post-translational modifications, particularly lysine acetylation and alkylation.
• Fine Chemical Synthesis: Used in the multi-step synthesis of specialized peptides and molecular probes.
• Reference Standard: Acts as a high-purity analytical standard for method development and quality control in related chemical analyses.

Basic Information

Product Name	N(Alpha)-Acetyl-ε-(2-Propenal)Lysine
CAS No.	99124-74-0
Molecular Formula	C11H18N2O4
Molecular Weight	242.27 g/mol
Synonyms	Nα-Acetyl-Nε-(2-propenal)lysine; N(Alpha)-Acetyl-N(Epsilon)-(2-Propenal)-L-Lysine; Acetylacrolein Lysine; Nα-Acetyl-Nε-(acryloyl)lysine; Lysine derivative, N-acetyl-N-(2-propenal)-; N-Acetyl-N'-(2-propenal)lysine; AGE Precursor Lysine Derivative; L-Lysine, N2-acetyl-N6-(2-propenal)-
EINECS	Contact for details

Quality Control

Our N(Alpha)-Acetyl-ε-(2-Propenal)Lysine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis to ensure it meets the exacting standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This compound is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider under an inert atmosphere. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.