Description

4-Benzyloxy-3,5-Difluorophenol is a fluorinated phenolic ether derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and high-purity building block for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Research: Serves as a precursor for developing new-generation herbicides and pesticides with enhanced efficacy and selectivity.
• Liquid Crystal Materials: Used in the production of fluorinated liquid crystals for high-performance displays (LCDs) due to its stable aromatic core and fluorine substituents.
• Polymer Chemistry: Acts as a monomer or modifier in the synthesis of specialty polymers, including polyarylates and epoxy resins, to impart specific thermal and chemical resistance.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and etherification processes to introduce the benzyloxy-difluorophenol moiety.
• Material Science Research: Investigated for use in organic semiconductors and photovoltaic materials due to its electron-withdrawing fluorine groups.

Basic Information

Product Name	4-Benzyloxy-3,5-Difluorophenol
CAS No.	99045-19-9
Molecular Formula	C₁₃H₁₀F₂O₂
Molecular Weight	236.21 g/mol
Synonyms	3,5-Difluoro-4-(phenylmethoxy)phenol; Phenol, 4-(benzyloxy)-3,5-difluoro-; 4-(Benzyloxy)-3,5-difluorophenol; 3,5-Difluoro-4-hydroxybenzyl phenyl ether; BDFP; 99045-19-9
EINECS	Contact for details

Quality Control

Our 4-Benzyloxy-3,5-Difluorophenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and scale-up. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.